What is the appearance called on the skin when HPV lesions are visualized after applying acetic acid?

What is the appearance called on the skin when HPV lesions are visualized after applying acetic acid?

• A. Acetowhite changes
• B. Erythematous patches
• C. Vesicular lesions
• D. Pigmented macules

Answer: (A)

Applying acetic acid to HPV-affected skin produces a whitening reaction known as acetowhite changes. The abnormal epithelium, which contains more protein and keratin, reflects light differently after the acid is applied, turning the area white and helping to visualize HPV lesions. This acetowhitening is the classic visual cue clinicians look for during examination. Erythematous patches are simply red from inflammation, vesicular lesions are small fluid-filled blisters, and pigmented macules are dark spots—none of these describe the whitening seen with the acetic acid test.

Applying acetic acid to HPV-affected skin produces a whitening reaction known as acetowhite changes. The abnormal epithelium, which contains more protein and keratin, reflects light differently after the acid is applied, turning the area white and helping to visualize HPV lesions. This acetowhitening is the classic visual cue clinicians look for during examination. Erythematous patches are simply red from inflammation, vesicular lesions are small fluid-filled blisters, and pigmented macules are dark spots—none of these describe the whitening seen with the acetic acid test.